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Atherosclerosis is the buildup of fats, cholesterol and other substances in and on the artery walls. This buildup is called plaque. The plaque can cause arteries to narrow, blocking blood flow. The plaque also can burst, leading to a blood clot.
Arteriosclerosis means “hardening of the arteries.” It’s a general medical term that refers to your normally flexible artery walls becoming hard or stiff. Your arteries are blood vessels that deliver oxygen-rich blood from your heart to all the organs and tissues in your body.
Pathophysiology. Monckeberg's arteriosclerosis. The lesions of arteriosclerosis begin as the intima (innermost layer of blood vessel wall) of the arterial wall start to fill up with the deposition of cellular wastes. As these start to mature, they can take different forms of arteriosclerosis.
Calcium deposits can narrow the arteries and increase the risk of a heart attack. The image on the left shows where the heart is typically located in the body (A). The middle image shows the area of the coronary calcium scan image (B). The image on the right shows a coronary calcium scan (C).
Diagnosis |. Treatment |. Key Points |. Atherosclerosis is characterized by patchy intimal plaques (atheromas) that encroach on the lumen of medium-sized and large arteries. The plaques contain lipids, inflammatory cells, smooth muscle cells, and connective tissue.
1 sty 2015 · The treatment of stenotic arterial segments relies on surgical grafting or medical minimally invasive procedures such as stenting. However, both methods often lead to intimal hyperplasia resulting from uncontrolled proliferation of vascular smooth myocytes.
