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2 dni temu · We conducted a phase 3, international, open-label, randomized, controlled trial. Men with stage T1 or T2 prostate cancer, a Gleason score of 3+4 or less, and a prostate-specific antigen (PSA ...
12 lut 2021 · Stereotactic body radiotherapy, i.e., high-precision radiotherapy delivering high doses within a few treatment sessions, is a very convenient treatment option, which has been shown to be effective and well tolerated in prostate cancer patients with low- or intermediate-risk profiles.
21 lut 2023 · Simultaneous integrated boost (SIB) stereotactic body radiotherapy (SBRT) for prostate and pelvic nodes in high risk, node positive and oligometastatic prostate cancers: Safety, efficacy and quality of life outcome measures.
As of 2020, SBRT is considered a standard of care option for any patient with low through very-high risk prostate cancer who is considering radiation therapy. The first patient to be treated with modern prostate SBRT was treated in December 2000.
5 cze 2020 · In accordance with risk stratification as defined by the National Comprehensive Cancer Network (NCCN), the definitive treatment options available for localized prostate cancer generally depend on a patient’s risk, as determined by prostate specific antigen (PSA) level, clinical T-stage, Gleason pattern, and number cores positive (National Compre...
7 lip 2022 · The PRIME trial (NCT03561961) is a phase III RCT comparing the efficacy of moderate hypofractionation (50 Gy to pelvis and 66–68 Gy to prostate in 25 fractions) with SBRT (25 Gy to pelvis, 35–36.5 Gy to prostate, and 30–35 Gy to gross nodes all in 5 fractions) in HRPC and N+ prostate cancer.
5 cze 2023 · The Radiosurgery Society endorses this case-based guide with the aim of providing a practical framework for delivering SBRT to the intact prostate, exemplified by two case studies. The article will explore common SBRT dose/fractionation schemes and dose constraints for organs-at-risk.
