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  1. 30 lip 2024 · Inhibiting IL-11 in mice extends lifespan and reduces aging signs, with potential implications for human aging treatments. Researchers from the Medical Research Council Laboratory of Medical Science and Imperial College London have discovered that ‘switching off’ a protein called IL-11 can increa

  2. 17 lip 2024 · The results, published in Nature, were dramatic, with mice given the anti-IL-11 drug from 75 weeks of age until death having their median lifespan extended by 22.4% in males and 25% in...

  3. 17 lip 2024 · The results, published in Nature, were dramatic, with mice given the anti-I-11 drug from 75 weeks of age until death having their median lifespan extended by 22.4% in males and 25% in females . The mice lived for an average of 155 weeks, compared with 120 weeks in untreated mice.

  4. 17 lip 2024 · Administration of anti-IL-11 to 75-week-old mice for 25 weeks improves metabolism and muscle function, and reduces ageing biomarkers and frailty across sexes.

  5. 18 lip 2024 · Anti-IL-11 therapy boosted metabolism, with the animals producing calorie-burning brown fat, not problematic stores of white fat, blocked the loss of muscle mass and strength, and protected...

  6. 19 lip 2024 · Mice given the anti-IL-11 drug from 75 weeks of age until death had their median lifespan extended by 22.4% in males and 25% in females. The treated mice lived for an average of 155 weeks, compared with 120 weeks in untreated mice.

  7. 17 lip 2024 · Key Facts: Lifespan Extension: Inhibiting IL-11 extends mice lifespan by 25%. Health Benefits: Reduced cancer and aging-related diseases observed. Future Potential: Could lead to anti-aging treatments in humans pending trials. Source: UK Research and Innovation.

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