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5 dni temu · Today, the focus has shifted from animal toxicity testing to non-animal for regulatory safety testing. This move is in line with the international 3Rs (Replacement, Reduction, and Refinement) principle and has also changed the regulator's perspective.
1 cze 2023 · The US Food and Drug Administration has reduced requirements for preclinical animal testing, leading to a surge of interest in organoids, tissue chips and in silico testing.
The project envisioned in the NC3Rs and WHO's cooperation, Holmes explained, will be articulated to address three major areas: (1) what is the extent of animal testing included within the collection of WHO recommendations for biologics and, of those, are there alternative methods already validated and approved elsewhere that should be included ...
15 sie 2022 · New data requirements are about to greatly increase animal testing, reigniting a heated debate about whether regulators can do better. But efforts to replace animal tests with alternative methods continue to falter because of a regulatory system that is not built for them.
30 sie 2021 · Research article. First published online August 30, 2021. Upholding the EU's Commitment to ‘Animal Testing as a Last Resort' Under REACH Requires a Paradigm Shift in How We Assess Chemical Safety to Close the Gap Between Regulatory Testing and Modern Safety Science.
4 lis 2022 · Biomedical advances fuel alternatives. Animal-based testing has been the gold standard for research for decades, and it remains an important requirement for establishing the safety and...
21 paź 2020 · Here we present a mini-review on the development of animal testing, as well as on alternative in vitro and in silico methods, that may at least partly replace animal experiments in the near future.
