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19 sie 2022 · A historical analysis was performed, in order to study how the mandatory animal studies in legislative requirements came about. This article reflects on the role that specific public health disasters played in the creation of (more) regulatory requirements for animal testing.
Transition to in vitro alternative methods from in vivo in vaccine release testing and characterization, the implementation of the consistency approach, and a drive towards international harmonization of regulatory requirements are most pressing ...
30 sie 2021 · Animal use for testing chemicals under REACH continues to increase, despite advances in non-animal safety science during the past 15 years. The application of modern science and technology, and the use of ‘next generation’ weight-of-evidence assessment approaches, are embedded in EU guidance for establishing the safety of cosmetics and ...
1 sty 2002 · Harmonization of test requirements and test methods, and availability and mutual recognition of test data and regulatory assessments, are required not only to minimize animal testing but also to ensure that responsible regulatory decisions are taken in an ethical, consistent, and timely manner.
1 sie 2023 · Such significant failures in clinical trials raise the question: what scientific evidence do we have that animal tests are the best way to predict and protect human health? It is about time the paradigm of animal testing as a “gold standard” in medicine was challenged, researched, and re-evaluated.
21 paź 2020 · Here we present a mini-review on the development of animal testing, as well as on alternative in vitro and in silico methods, that may at least partly replace animal experiments in the near future.
7 wrz 2011 · Today, these guidelines provide a platform for the protection of human research subjects, including the principles of respect, beneficence, and justice, as well as special protections for vulnerable populations. Laws to protect animals in research have also been established.
