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19 sie 2022 · The contemporary pharmaceutical industry is voicing growing concerns about the translatability and reproducibility of animal models. In addition, the usefulness of certain of the required regulatory safety tests in animals is being increasingly questioned.
This article reviews the use of non-human animals in biomedical research from a historical viewpoint, providing an insight into the most relevant social and moral issues on this topic across time, as well as to how the current paradigm for ethically ...
21 paź 2020 · Here we present a mini-review on the development of animal testing, as well as on alternative in vitro and in silico methods, that may at least partly replace animal experiments in the near future.
1 sie 2023 · Such significant failures in clinical trials raise the question: what scientific evidence do we have that animal tests are the best way to predict and protect human health? It is about time the paradigm of animal testing as a “gold standard” in medicine was challenged, researched, and re-evaluated.
4 sty 2017 · In the absence of contrary documentation, we infer that up until the 20th century testing of pharmaceutical preparations was conducted almost exclusively in humans, that testing in animals for efficacy occurred infrequently, and testing in animals for safety occurred rarely if at all.
For a variety of reasons very well researched and analyzed by historians Richard French (1975) and James Turner (1980) (among others), the public found the idea of deliberately inflicting harm on animals in order to learn more about health and medi-cine particularly disturbing.
16 gru 2020 · Through the analysis of fundamental philosophical concepts and some practical examples, we propose a view according to which laboratory animals experimentation become ethically acceptable as far as it is guided by the goal of improving humans and other animal species (i.e., pets) life.
