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This article reviews the use of non-human animals in biomedical research from a historical viewpoint, providing an insight into the most relevant social and moral issues on this topic across time, as well as to how the current paradigm for ethically ...
19 sie 2022 · The contemporary pharmaceutical industry is voicing growing concerns about the translatability and reproducibility of animal models. In addition, the usefulness of certain of the required regulatory safety tests in animals is being increasingly questioned.
21 paź 2020 · Here we present a mini-review on the development of animal testing, as well as on alternative in vitro and in silico methods, that may at least partly replace animal experiments in the near future.
5 lut 2011 · Animal studies include in vivo tumour growth and survival assays in metastatic and orthotopic models, in vivo imaging assays [3] and early pharmacokinetic evaluation by appropriate screening ...
1 lis 2017 · In light of this, this article aims to discuss the importance of animal models in diverse lines of biomedical research by analyzing the contributions of the various species utilized in science...
1 sie 2023 · The regulatory transition to animal-free testing appears to move painstakingly slow, but it could occur more rapidly under the right conditions. For instance, there was rapid regulatory acceptance of alternatives during the Covid-19 pandemic for the conditional market release of novel mRNA vaccines.
5 kwi 2017 · Advice on use of the check-list is available on the Norecopa website, with links to guidelines for animal research and testing, at https:// norecopa.no/PREPARE. Keywords guidelines, planning, design, animal experiments, animal research. Date received: 5 April 2017; accepted: 27 June 2017.
