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19 sie 2022 · The contemporary pharmaceutical industry is voicing growing concerns about the translatability and reproducibility of animal models. In addition, the usefulness of certain of the required regulatory safety tests in animals is being increasingly questioned.
This article reviews the use of non-human animals in biomedical research from a historical viewpoint, providing an insight into the most relevant social and moral issues on this topic across time, as well as to how the current paradigm for ethically ...
21 paź 2020 · Today, animal experiments are widely used in medical, biomedical and veterinary research, and are essential means of drug development and preclinical testing, including toxicology and safety studies.
13 sty 2024 · Scholars recommend regulators promote alternatives to experiments conducted on animals. Over 110 million animals die in U.S. laboratories used for animal testing every year. Their deaths are painful, as lab animals subjected to testing are often immobilized, mutilated, and exposed to toxic substances.
1 sie 2023 · Such significant failures in clinical trials raise the question: what scientific evidence do we have that animal tests are the best way to predict and protect human health? It is about time the paradigm of animal testing as a “gold standard” in medicine was challenged, researched, and re-evaluated.
When a human-toxic drug is identified as “safe” by animal testing, the most likely outcome by far is that the drug will fail in clinical testing, often due to unacceptable adverse human effects, and sometimes significantly harming volunteer research subjects in the process.
11 paź 2022 · In this article, I present four examples of animal tests that were introduced in the past to protect patients and consumers, and I discuss attempts to replace those animal tests with...
