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This article reviews the use of non-human animals in biomedical research from a historical viewpoint, providing an insight into the most relevant social and moral issues on this topic across time, as well as to how the current paradigm for ethically ...
19 sie 2022 · Abstract. The contemporary pharmaceutical industry is voicing growing concerns about the translatability and reproducibility of animal models. In addition, the usefulness of certain of the required regulatory safety tests in animals is being increasingly questioned.
21 paź 2020 · Here we present a mini-review on the development of animal testing, as well as on alternative in vitro and in silico methods, that may at least partly replace animal experiments in the near future.
13 sty 2024 · In an article in the University of Illinois Chicago Law Review, Lenore Montanaro of the Roger Williams University School of Law argues that regulators should mandate the reporting of lab animals used in research, regardless of species, promoting the reduction of animal testing.
1 sie 2023 · The FD&C Act itself was passed following a large death toll from a chemical accident, and not based on evidence suggesting human safety would be improved by testing on animal models. 1 Still, the transition to the acceptance of animal-free methods in legislation is positive news.
1 lis 2017 · Due to their relevance, this article aims to discuss the importance of animal models in diverse lines of biomedical research by analyzing the contributions of the various species utilized in ...
When a human-toxic drug is identified as “safe” by animal testing, the most likely outcome by far is that the drug will fail in clinical testing, often due to unacceptable adverse human effects, and sometimes significantly harming volunteer research subjects in the process.
