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In the chemical industry, aniline is used as a parent substance for the synthesis of many compounds, including isocyanates, dyes and pigments, antioxidants, and accelerators in rubber processing, pharmaceuticals, varnishes, perfumes, photographic chemicals, herbicides, and fungicides (aniline is no longer approved for pesticide use in the ...
18 sie 2010 · Aniline, phenylamine or aminobenzene is an organic compound with the formula C6H5NH2. Consisting of an amine attached to a benzene ring, aniline is the prototypical aromatic amine. Being a precursor to many industrial chemicals, its main use is in the manufacture of precursors to polyurethane.
10 paź 2020 · Among the “structural alerts” responsible, anilines are well-known to undergo deleterious metabolic processing, yet isosteric replacement strategies remain limited. Herein we discuss current art and potential new avenues of saturated isosteres to mitigate aniline-related toxicities.
Aniline is a colorless, liquid, volatile, aromatic amine with a putrid odor that is currently used in urethane production.
A voltage-gated sodium channel blocker used for management of atrial or ventricular fibrillation, atrial flutter, and ventricular tachycardia, that is no longer used due to proarrhythmic adverse effects.
The discovery of the aniline dyes in the 19th century and contemporary investigation of their use as biological stains by scientists such as Koch and Ehrlich led to the idea of selectivity and formed the basis of modern chemotherapy; several of these dyes remain in pharmacopoeias.
2 sie 2015 · The present study is one of the first to provide reliable urinary excretion factors for aniline and its metabolites in humans after oral dosage, including data on the predominant urinary metabolite N -acetyl-4-aminophenol, also known as an analgesic under the name paracetamol/acetaminophen.
