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Anaphylaxis is defined as the acute onset of a hypersensitivity reaction causing the release of mediators from mast cells and basophils. Anaphylaxis may be a life-threatening condition that can involve one or more organ systems. Often, a specific cause for anaphylaxis is not known.
Abstract. Objective – To review and summarize current information regarding the pathophysiology and clinical man-ifestations associated with anaphylaxis in dogs and cats. The etiology, diagnosis, treatment, and prognosis is discussed. Etiology – Anaphylaxis is a systemic, type I hypersensitivity reaction that often has fatal consequences.
15 lip 2013 · To review and summarize current information regarding the pathophysiology and clinical manifestations associated with anaphylaxis in dogs and cats. The etiology, diagnosis, treatment, and prognosis is discussed.
Adverse Reactions Chronic use (>2 weeks) can lead to crystalluria, haematuria, urinary obstruction, haematopoietic disorders (anaemia, leukopaenia, thrombocytopaenia) and dermatological reactions. Do not use in Doberman Pinschers. ~0.25% of dogs may suffer idiosyncratic drug reactions 10-21 days after exposure, including
8 maj 2020 · Anaphylactic (AX)-related gallbladder edema is specific to canines because the canine shock organ, where the highest concentration of mast cells are located, is their liver and gastrointestinal tract.
Nearly any antigen that stimulates mast cells and basophils can cause anaphylaxis. Clinical signs typically manifest soon after antigenic exposure (5-30 minutes) and progress rapidly over minutes to hours. Sometimes, anaphylactic reactions may take hours to manifest or even be biphasic in nature.
An anaphylactic reaction or anaphylaxis is an immediate, severe, sometimes life-threatening hypersensitivity (allergic) reaction to a foreign substance, especially a foreign protein, known as an allergen or antigen.
