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Antibiotic resistance is classified into three broad groups according to the sensitivity pattern to the different antibiotic classes, namely, pan-drug-resistant (PDR), extensively drug-resistant (XDR), and multidrug-resistant (MDR) microbial infections.
Currently, the efficacy of antibiotics is severely affected by the emergence of the antimicrobial resistance phenomenon, leading to increased morbidity and mortality worldwide. Multidrug-resistant pathogens are found not only in hospital settings, ...
1 gru 2021 · T cells, which secrete numerous interleukins (ILs) that activate antimicrobial activities in mononuclear phagocytes, are largely responsible for acquired resistance to intracellular microorganisms. The role of ILs in antimicrobial infection has been clarified to experimental infection of mice with Mycobacterium bovis and Listeria monocytogenes.
Ampicillin (AMP), a semi-synthetic β-lactam antibiotics, is widely used to treat of human and livestock E. coli infection, but recently its resistance rate has increased. 1–3 AMP works on the active replicating stage of bacteria, inhibiting the synthesis of bacterial cell wall.
3 cze 2024 · The rise of antibiotic resistance and a dwindling antimicrobial pipeline have been recognized as emerging threats to public health.
12 lut 2022 · Antimicrobial resistance (AMR) poses a major threat to human health around the world. Previous publications have estimated the effect of AMR on incidence, deaths, hospital length of stay, and health-care costs for specific pathogen–drug combinations in select locations.
21 lis 2023 · For urinary tract infections caused by E. coli, 1 in 5 cases exhibited reduced susceptibility to standard antibiotics like ampicillin, co-trimoxazole, and fluoroquinolones in 2020. This is making it harder to effectively treat common infections.
