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  1. 28 lip 2024 · Explore the mechanisms and detection methods of ampicillin resistance in bacteria, focusing on genetic mutations and beta-lactamase enzymes.

  2. The journey of antibiotic development and resistance. Key dates for introduction of different penicillin classes and corresponding emergence of resistance are shown (top and bottom, respectively). Examples of different generations of penicillin are indicated and color-coded as in Figure 3.

  3. 1 cze 2024 · Resistant drug uptake, target site change, efflux pump mechanism, and target site mutation are examples of resistance mechanisms. The presence of resistant bacteria and antibiotic residues in the environment requires urgent global action to combat antimicrobial resistance (AMR).

  4. 12 cze 2024 · Antibiotic resistance (AMR) represents genetic and biochemical strategies that evade and overcome antibiotics. Abbas, Barkhouse et al. discuss how AMR is a survival trait evolved by bacteria over millennia and readily mobilized across bacterial populations; consequently, AMR is a fundamental threat to how we practice modern medicine and ...

  5. 21 lis 2022 · Antimicrobial resistance (AMR) is a major global health challenge, causing substantial morbidity and death globally. Understanding the molecular mechanisms that underlie resistance can aid in...

  6. 30 sty 2022 · Here, we aim to describe the history of antibiotics and antimicrobial resistance, and the various innovative new leads and related mechanisms of action expected to replenish the pipeline and shift the chase and the race between the spread of AMR and innovative antibiotics discovery.

  7. Resistance to ampicillin was extremely common in ST and MST, being reported in 44/49 (89.8%) and 87/89 (97.8%) isolates, respectively. Also, resistance to sulphonamides and tetracycline was extremely widespread, reaching 95.8% (23/24) and 78.7% (37/47) in ST and 95.7% (67/70) and 97.8% (89/91) in MST, respectively.