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31 sie 2000 · In men with osteoporosis, alendronate significantly increases spine, hip, and total-body bone mineral density and helps prevent vertebral fractures and decreases in height.
7 sie 2024 · Alendronate is used in the treatment and prevention of osteoporosis in postmenopausal women and men. Alendronate may also be used to treat glucocorticoid-induced osteoporosis and Paget's disease of the bone. Alendronate may also be used to treat adverse skeletal effects caused by some cancers.
Key facts. Alendronic acid is good for your bones – it makes them stronger and less likely to break. You'll usually take it as a tablet or liquid, once a week. Take alendronic acid first thing in the morning, before you have anything to eat or drink and before you take any other medicines.
Alendronate (alendronic acid), a nitrogen-containing bisphosphonate that inhibits bone resorption by osteoclasts, was synthesized during the 1970s. In the present review, we discuss the pharmacokinetics, mechanism of action, adverse effects, contraindications, and toxicity monitoring of alendronate.
Alendronate may be suitable if you have osteoporosis, or if your risk of breaking a bone is high enough to need a drug treatment. It is licensed for use in women who have been through the menopause, and for men. Doctors will occasionally offer it to younger women. Alendronate tablets are usually the first treatment that people are offered.
Alendronic acid 70mg administered once weekly is an effective and convenient alternative to daily dosing for the treatment of male osteoporosis.
23 lis 2021 · Bisphosphonates are the mainstay in therapeutic option for the prevention and treatment of osteoporosis (1). alendronate and etidronate are licensed for the treatment of corticosteroid-induced osteoporosis in men (3).