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8 maj 2023 · This activity reviews updates on the recommended use of furosemide, the mechanism of action, indications, contraindications, adverse effects, toxicity, and other key factors (e.g., off-label uses, dosing, pharmacokinetics, monitoring, relevant interactions) profile.
(ii) Adverse effects. The most common adverse effects of furosemide are fluid and electrolyte imbalance, including hyponatraemia, hypokalaemia and hypochloraemic alkalosis. Hyperuricaemia is relatively common, and a variety of uncommon adverse reactions have been reported (see Reynolds, 1989).
8 maj 2023 · This activity reviews updates on the recommended use of furosemide, the mechanism of action, indications, contraindications, adverse effects, toxicity, and other key factors (e.g., off-label uses, dosing, pharmacokinetics, monitoring, relevant interactions) profile.
1 maj 2016 · Undesirable consequences of furosemide, such as worsening of kidney function and unpredictable effects on sodium balance, led to this critical evaluation of how inhibition of NKCC affects renal and cardiovascular physiology.
Adverse Effects: Includes gastrointestinal, systemic, central nervous system, hematologic, dermatologic, cardiovascular, renal, and metabolic disturbances. Contraindications: Avoid in patients...
Serious drug interactions: furosemide-induced electrolyte disturbances, particularly hypokalamia, can increase the risk of: • cardiac arrhythmia and death with drugs known to prolong the QT interval, e.g. citalopram, methadone. • digoxin toxicity. • lithium toxicity (possibly). 38.
Daily net fluid balance was used as the objective marker for development of tolerance. Net fluid balance (mL/kg/mg) was defined as the difference in a patient's daily intake and urine output (mL), normalized by weight (kg) and total daily dose of furosemide (mg).
