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4 lip 2024 · Acute disseminated encephalomyelitis (ADEM), as the name would suggest, is featured by a monophasic acute inflammation and demyelination of white matter typically following a recent (1-2 weeks prior) viral infection or vaccination 4,6.
In the acute stages, ADEM is characterized histologically by perivenous edema, demyelination, and infiltration with macrophages and lymphocytes, with relative axonal sparing, whereas the late course of the disease is characterized by perivascular gliosis.
27 sie 2021 · Acute disseminated encephalomyelitis (ADEM) is an inflammatory demyelinating disease of the CNS, characterized by fulminant multifocal neurologic injury and distinct neuropathologic findings. 1 ADEM is classically thought to be preceded by vaccination or a systemic infection, of which upper respiratory tract infections are most commonly ...
8 cze 2022 · Acute disseminated encephalomyelitis (ADEM) is a rare immune-mediated inflammatory demyelinating disorder of the central nervous system (CNS) (1, 2) that was first described in a patient after smallpox infection 250 years ago (3).
This case demonstrates typical imaging features of ADEM, which although characterized as a monophasic illness, individual lesions are not all at the same stage of evolution, thus some small or inapparent lesions early on can be seen to appear and mature even while other lesions regress.
26 sty 2024 · Acute disseminated encephalomyelitis (ADEM), or post-infectious encephalomyelitis, is an acute, intense, polyfocal, inflammatory autoimmune disorder affecting the central nervous system (CNS). Children are predominantly affected, yet adult cases are not uncommon.
28 mar 2017 · In the acute stages, ADEM is characterized histologically by perivenous edema, demyelination, and infiltration with macrophages and lymphocytes, with relative axonal sparing, whereas the late course of the disease is characterized by perivascular gliosis.
