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Ferritin is the main iron storage protein. The normal range is 15 – 300 µg/dL. The sensitivity and specificity of the test vary depending on cut-off levels used to define iron deficiency; at a cut-off level of 15µg/L, the test is highly specific for iron deficiency, but lacks sensitivity.
- Management of Iron Deficiency
Oral iron supplementation is usually sufficient for most...
- Clinical and Laboratory Features
Alternatively, anaemia may be incidentally detected on a...
- Iron Homeostasis
Body Iron Distribution. 1. Iron is absorbed in the duodenum...
- Autoimmune Haemolytic Anaemia
If a patient with AIHA presents with acute, severe...
- Haemolytic Anaemia Quiz
Iron Regulation and Iron Deficiency 4 Topics | 1 Quiz Iron...
- Nomenclature
Haemoglobinopathy refers to a genetic abnormality which...
- Haemoglobinopathies
Understand the indications for starting iron-chelating...
- Normal Haematopoiesis
An overview of normal haematopoiesis, including...
- Management of Iron Deficiency
Normal Range: MCV typically falls within the range of 80-100 fL. Microcytosis (low MCV): An MCV value below 80 fL suggests microcytic red blood cells and is a strong indicator of iron deficiency anemia. However, other conditions like thalassemia can also cause microcytosis.
Total body iron deficit/cumulative iron dose (mg) = body weight* (kg) x (target Hb – actual Hb in g/L) x 0.24** + iron depot (mg)*** *Use ideal body weight in overweight patients.
6 gru 2019 · Our approach to ID and iron deficiency anemia (IDA) involves three steps (I 3): (1) identification of ID/IDA, (2) investigation of and management of the underlying etiology of ID, and (3) iron repletion. Iron repletion options include oral and intravenous (IV) iron formulations.
Iron deficiency anemia is a form of anemia due to the lack of sufficient iron to form normal red blood cells. Iron deficiency anemia is typically caused by inadequate intake of iron, chronic blood loss, or a combination of both. Iron deficiency anemia is the most common cause of anemia in the world.
ron deficiency or iron deficiency anaemia. Although the initial rise in haemoglobin (Hb) is more rapid with parenteral iron, the rise in Hb at 12 weeks is similar .
Signs of anemia itself are neither sensitive nor specific; however, pallor is common with severe anemia (ie, hemoglobin < 7 g/dL [< 70 g/L]). Signs of many underlying disorders are more diagnostically accurate than are signs of anemia.