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5 kwi 2024 · Systemic sclerosis, also known as scleroderma, is a rare connective tissue disorder with an unknown and complex pathogenesis. Scleroderma can be divided into 2 primary forms—localized scleroderma (including morphea, linear scleroderma, and scleroderma en coup de sabre) and systemic sclerosis.
Systemic sclerosis, also known as scleroderma, is a rare and complex autoimmune connective-tissue disease. Once considered an untreatable and unpredictable condition, research advancements have improved our understanding of its disease pathogenesis and clinical phenotypes and expanded our treatment armamentarium.
Scleroderma makes your body produce too much collagen, a protein that you need for healthy skin and tissue. It’s an autoimmune condition, which means your immune system attacks your body instead of protecting it. Scleroderma can cause lots of symptoms and affect tissue throughout your body.
15 cze 2024 · Scleroderma (sklair-oh-DUR-muh), also known as systemic sclerosis, is a group of rare diseases that involve the hardening and tightening of the skin. Scleroderma also may cause problems in the blood vessels, internal organs and digestive tract.
16 sie 2024 · Systemic sclerosis (scleroderma) is a non-contagious, chronic, multi-system disease. Initial symptoms are non-specific and include fatigue, vague musculoskeletal complaints, diffuse swelling of hands, and Raynaud's phenomenon. Aetiology and pathogenesis are unknown.
Scleroderma is a rheumatic disease, which means patients may have inflammation, pain, swelling and stiffness in the joints, tendons, ligaments, bones, muscles and/or tissues. It’s also an autoimmune disease.
There are two major clinical subsets of scleroderma: (i) systemic sclerosis (SSc) is a complex systemic autoimmune disorder characterized by inflammation, vasculopathy, and excessive fibrosis of the skin and multiple internal organs and (ii) localized scleroderma (LoS), also known as morphea, is confined to the skin and/or subcutaneous tissues ...
