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5 dni temu · The journal aims to bring together clinical and experimental aspects of renal failure to present timely, practical information on a variety of topics: Pathology and pathophysiology of acute renal failure; Nephrotoxicity of drugs and other substances; Prevention, treatment, and therapy of renal failure
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Renal Failure, Volume 46, Issue 2 (2024) See all volumes and...
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Kidney Failure – Knowledge and References – Taylor & Francis. Kidney failure, also known as end-stage renal disease (ESRD), is a condition in which the kidneys are no longer able to function properly and require renal replacement therapy (RRT) to sustain life.
Acute kidney failure is defined as a sudden, sustained impairment of kidney function, typically for periods of 1–7 days, resulting in reduced glomerular filtration rate, urinary volume, electrolyte imbalance and impaired pH regulation.
Acute renal failure (ARF) is a syndrome characterized by abrupt deterioration of renal function with a resultant inability to regulate solute and water balance. ARF can be caused by acute prerenal failure, primary (intrinsic) failure, or postrenal failure.
Many clinically accepted definitions are used to identify when an increase in serum creatinine should be classified as acute renal failure, including an increase in creatinine of 0.5 mg/dL in 24 hours or a doubling of creatinine in 1 to 3 days.
Renal blood flow is around 20% of cardiac output (1000 ml/min in an adult) and renal plasma flow (RPF) is approximately 600 ml/min. The glomerulus filters 125 ml/min of renal plasma. This glomerular filtration rate (GFR) is a much more reliable marker of renal function than plasma creatinine.
Renal Failure. The primary focus of Renal Failure is acute kidney injury (AKI). This includes the basic sciences and those derived from human studies on the subject. There is a critical need to support the drive for research in this field. The high mortality of AKI in the critically ill is unacceptable.
