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Quinine is a medication used to treat malaria and babesiosis. [5] This includes the treatment of malaria due to Plasmodium falciparum that is resistant to chloroquine when artesunate is not available.
24 maj 2011 · Quinine remains an important anti-malarial drug almost 400 years after its effectiveness was first documented. However, its continued use is challenged by its poor tolerability, poor compliance with complex dosing regimens, and the availability of more efficacious anti-malarial drugs.
Quinine is used parenterally to treat life-threatening infections caused by chloroquine-resistant Plasmodium falciparum malaria. Quinine acts as a blood schizonticide although it also has gametocytocidal activity against P. vivax and P. malariae.
22 mar 2019 · Here the range of anti-malarial medicines developed over the years are reviewed, beginning with the discovery of quinine in the early 1800s, through to modern day ACT and the recently-approved tafenoquine.
10 lut 2022 · Summary of quinine pharmacokinetic studies in children with malaria (uncomplicated malaria and complicated malaria). Pharmacokinetic parameters (Cmax and systemic exposure) are presented as mean + SD or mean or median (range) or median values.
12 gru 2013 · Typically, the rapid action of the artemisinin component is combined with an agent exhibiting a more sustained antimalarial effect (often a synthetic quinoline). Thus, the exploits of the earliest drug hunters continue to pay dividends today via the chemical progeny of quinine and artemisinin.
23 wrz 2024 · quinine, drug obtained from cinchona bark that is used chiefly in the treatment of malaria, an infection caused by the protozoan parasite Plasmodium, which is transmitted to humans by the bite of various species of mosquitoes.
