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13 cze 2024 · Pathology and pathobiology: a brief overview. Pulmonary vascular remodelling is a hallmark shared by all forms of pulmonary hypertension (PH), characterised by a spectrum of structural and functional changes occurring primarily in the distal part of the pulmonary circulation. These changes can predominantly affect the pulmonary arterioles in ...
- Pathology and pathobiology of pulmonary hypertension: state of the art ...
Pulmonary hypertension (PH) encompasses a group of severe...
- Pathology and pathobiology of pulmonary hypertension: state of the art ...
16 maj 2018 · Pulmonary hypertension (PH) consists of a group of diseases with a resting mean pulmonary artery pressure (mPAP) ≥ 25 mmHg as measured with right heart catheterization . Since 1998, major revisions in the classification of PH have categorised the disease based on the anatomical site and aetiology.
The underlying molecular pathogenesis of pulmonary hypertension is a complex and multifactorial process, but can be characterised by several hallmarks: inflammation, impaired angiogenesis, metabolic alterations, genetic or epigenetic abnormalities, influence of sex and sex hormones, and abnormalities in the right ventricle.
Pulmonary hypertension (PH) encompasses a group of severe clinical entities, such as pulmonary arterial hypertension (PAH) and chronic thromboembolic PH (CTEPH), in which loss and obstructive remodelling of the pulmonary vascular bed is responsible for the rise in pulmonary arterial pressure and
29 sie 2024 · In recent years, major advances have been made in the understanding of the cellular and molecular mechanisms driving pulmonary vascular remodelling in various forms of pulmonary hypertension,...
1 paź 2013 · Pulmonary arterial hypertension (PAH) is a progressive and fatal vascular disease in which high blood pressure in the pulmonary artery and remodeling of the pulmonary vasculature ensues.
This review focuses on the relatively rare form of pulmonary arte-rial hypertension (group 1). Immense progress has been achieved in gaining an understanding of the mechanisms, natural...
