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7 maj 2021 · Most frequent clinical presentation: flaccid bullae or crusted erosions involving skin or mucosa. Prototypic histopathological feature: intraepidemal acantholysis with intact basal layer (tombstone sign) and intraepidermal eosinophils. Direct immunofluorescence shows intercellular IgG / IgA and C3.
The histology may show subcorneal separation and superficial epidermal intercellular IgG deposition simulating pemphigus foliaceus. Typically cases demonstrate more prominent eosinophilic spongiosis with intraepidermal blister formation and occasionally subcorneal neutrophilic pustulation.
8 sie 2023 · This activity describes the evaluation and management of pemphigus foliaceus and highlights the role of the interprofessional team in improving care for affected patients. Objectives: Review the pathophysiology of pemphigus foliaceus. Describe the typical presentation of pemphigus foliaceus.
Pęcherzyca liściasta (łac. pemphigus foliaceus) – autoimmunologiczna choroba skóry, należąca do dermatoz pęcherzowych, charakteryzująca się zmianami nadżerkowo-złuszczającymi, krótkotrwałymi pęcherzami i powolnym przebiegiem. Zmiany nie występują na błonach śluzowych.
Ultimately, the diagnosis of PF is based on three criteria: (1) The overall clinical picture, including patient history and physical exam; (2) The histopathological findings of the biopsy; and (3) The presence of autoantibodies as detected by direct and indirect immunofluorescent studies.
Pemphigus is a skin condition that causes intraepidermal separation of keratinocytes. Multiple types of pemphigus exist, including pemphigus vulgaris and pemphigus foliaceus. These can be differentiated by histopathology, clinical presentation, appearance of lesions, and antibodies, among other factors. It is important to distinguish between ...
In this paper I am presenting detailed histopathological study of pemphigus foliaceus. Review of Literature. The problem of histopathological differentiation of bullous diseases has been focused on pemphigus, dermatitis herpetiformis, and erythema multiforme. In the classical textbooks of skin pathology 1-4 it is stated that
