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  1. Women with more severe OHSS may require inpatient treatment to manage the symptoms and reduce the risk of further complications. Prevention of OHSS is outside the scope of this guideline and is covered by guidance from the British Fertility Society.

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  2. It is recommended to counsel patients with elevated antimullerian hormone levels, polycystic ovary syndrome (PCOS), and anticipated high oocyte yields that they are at increased risk for ovarian hyperstimulation syndrome (OHSS). Interventions to reduce OHSS risk should be focused on this patient population.

  3. Women with severe or critical OHSS and those admitted with OHSS should receive LMWH prophylaxis. The duration of LMWH prophylaxis should be individualised according to patient risk factors and outcome of treatment.

  4. INTRODUCTION. Ovarian hyperstimulation syndrome (OHSS) is an uncommon but serious complication associated with controlled ovarian stimulation during assisted reproductive technology (ART). Mode-rate-to-severe OHSS occurs in approxi-mately 1% –5% of cycles (1 –5).

  5. Ovarian hyperstimulation syndrome (OHSS) is an uncommon but serious complication associated with assisted reproductive technology (ART). This systematic review aims to identify who is at high risk, how to prevent OHSS, and the treatment for existing OHSS.

  6. Treatment of moderate OHSS consists of observation, bed rest, provision of adequate fluids and sonographic monitoring of the size of cysts. Serum electrolyte concentrations, hematocrits and creatinine levels should also be evaluated.

  7. RECOMMENDATIONS. It is recommended to counsel patients with elevated antim€ullerian hormone levels, polycystic ovary syndrome (PCOS), and anticipated high oocyte yields that they are at increased risk for ovarian hyperstimulation syn-drome (OHSS). Interventions to reduce OHSS risk should be focused on this patient population.

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