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  1. 3 mar 2022 · In this narrative review, we aim to discuss the pharmacological properties of nitrous oxide, the potential advantages and drawbacks of the use of nitrous oxide in children, address the neurodevelopmental and other systemic effects, and throw light on the evidence regarding the safety of nitrous oxide use and its current role in pediatric ...

  2. The choice of carrier gas is influenced by pharmacological principles and the clinical scenario: oxygen alone maximises oxygen reserve and is typically used when difficulty with the airway is anticipated, whereas nitrous oxide (N 2 O) offers analgesia and a superior speed of induction.

  3. 12 maj 2023 · Kehar M, Yadav SP, Sachdeva A, Gupta S. Nitrous oxide is as effective as ketamine-midazolam sedation for procedure related pain in children with cancer. Ped Blood Cancer. 2012;59(6):1117. Google Scholar

  4. 2 dni temu · The use of nitrous oxide during selected paediatric procedures was judged by the nurse in charge of care to be highly effective in 81 % of cases. Adverse effects led to stoppage of the procedure in 2 % of cases.

  5. 9 wrz 2019 · Nitrous oxide is a useful option for children who require procedural sedation, and means that more procedures can be performed without general anaesthesia.

  6. 23 wrz 2023 · Nitrous oxide (N2O) is an inhaled analgesic/anxiolytic gas with ample evidence supporting its safety and efficacy in children. However, its prevalence of use remains low, while its indications in paediatric emergency departments (EDs) across Canada remain unknown.

  7. The objective of this study was to synthesize indication-based evidence for N2O for distress and pain in children. Study design. We included trials of N2O in participants 0–21 years, reporting distress or pain for emergency department procedures. The primary outcome was procedural distress.

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