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  1. Natriuretic peptides, which are activated in heart failure, play an important cardioprotective role. The most notable of the cardioprotective natriuretic peptides are atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP), which are abundantly expressed and secreted in the atrium and v ….

  2. 1 lis 2021 · In this paper, I will present findings to date on the physiological role of the natriuretic peptide system in maintaining cardiovascular homeostasis and the pathophysiological implications for heart failure onset and progression, as well as review the clinical significance and potential of natriuretic peptides as diagnostic and/or therapeutic ...

  3. 26 kwi 2023 · Understanding the role of natriuretic peptides beyond the cardiovascular system. Natriuretic peptides are known to have protective effects not only on the heart but also on multiple organs via the cGMP–protein kinase G signaling pathway.

  4. After its discovery in the early 1980s, the natriuretic peptide (NP) system has been extensively characterized and its potential influence in the development and progression of heart failure (HF) has been investigated.

  5. This article overviews the natriuretic peptides (NPs) system, its role and the development of NP-based treatment of heart failure (HF). Keywords: bradykinin, heart failure, LCZ696 (sacubitril/valsartan), natriuretic peptides, neprilysin, neuroendocrine syndrome.

  6. 17 paź 2022 · Natriuretic peptides, brain (B-type) natriuretic peptide (BNP) and N-terminal prohormone of brain natriuretic peptide (NT-proBNP) are globally and most often used for the diagnosis of heart failure (HF).

  7. 27 paź 2015 · Differential regulation of membrane guanylyl cyclases in congestive heart failure: natriuretic peptide receptor (NPR)‐B, Not NPR‐A, is the predominant natriuretic peptide receptor in the failing heart.

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