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10 lis 2020 · The process by which cancer cells spread to other parts of the body is called metastasis. When observed under a microscope and tested in other ways, metastatic cancer cells have features like that of the primary cancer and not like the cells in the place where the metastatic cancer is found.
12 mar 2020 · The development of secondary tumors in a part of the body that is far from the original primary cancer is termed “metastasis.” Despite metastasis being the key cause of failure of cancer therapy...
13 kwi 2023 · Metastasis, the growth of cancer cells in organs distant from the one in which they originated, is the ultimate and most lethal manifestation of cancer. The vast majority of cancer patients die as a consequence of their metastatic disease and not due to primary tumors.
13 kwi 2023 · Metastasis requires the acquisition of a succession of traits to disseminate, variably enter and exit dormancy, and colonize distant organs. The success of these events is driven by clonal selection, the potential of metastatic cells to dynamically transition into distinct states, and their ability to co-opt the immune environment.
13 sty 2021 · Discerning the biological differences between micro- and macrometastases, targeting the vulnerabilities of metastatic cancer cells and exploiting the properties of metastatic tumor ...
26 lip 2018 · At the metastatic niche, microenvironmental TGF-β from tumour or stromal cells induces CAFs to secrete ECM niche components, such as periostin and tenascin-C, to maintain the stemness of ...
8 sie 2022 · Metastasis is an extremely inefficient process constituted by consecutive harsh steps. The mobilized cancer cells have to cope with various kinds of stresses to successfully translocate from the primary site to distal organs and colonize there.
