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Patients with symptomatic brain metastases should receive local therapy regardless of the systemic therapy used. For patients with asymptomatic brain metastases, local therapy should not be deferred unless deferral is specifically recommended in this guideline.
29 lis 2023 · Metastases are the most common intracranial tumors in adults, accounting for more than one-half of all intracranial tumors. The primary approaches to the treatment of brain metastases include surgery, stereotactic radiosurgery (SRS), and whole brain radiation therapy (WBRT).
5 sie 2021 · This Clinical Practice Guideline provides management recommendations for patients with brain metastases from solid tumours. •. The guideline covers clinical and pathological diagnosis, staging and risk assessment, treatment and follow-up. •. Treatment and management algorithms are provided. •.
Treatment may involve a combination of surgery, radiotherapy, and systemic medical therapy depending on the patient’s neurologic status, performance status, and overall oncologic burden. Advances in these domains have substantially impacted the management of brain metastases and improved performance status and survival for some patients.
21 gru 2021 · Patients with symptomatic brain metastases should receive local therapy regardless of the systemic therapy used. For patients with asymptomatic brain metastases, local therapy should not be deferred unless deferral is specifically recommended in this guideline.
25 paź 2022 · Treatment for brain metastases can help ease symptoms, slow tumor growth and extend life. Even with successful treatment, brain metastases often recur, so your doctor will recommend close follow-up after treatment.
This multisociety guideline addresses the role of surgery, radiation therapy, and systemic therapy in the treatment of patients with brain metastases. For each of these therapies, a set of clinical questions was considered (summarized below).