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1. medicalxpress.com › news › 2024-07-scientists-interleukin-key-driver-agingScientists identify interleukin-11 as key driver of aging

   medicalxpress.com › news › 2024-07-scientists-interleukin-key-driver-aging

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   17 lip 2024 · The team demonstrated in preclinical models that the protein interleukin-11 (IL-11) actively promotes aging and that giving an anti-IL-11 therapy not only counteracts the deleterious...

2. medicalxpress.com › news › 2024-07-scientists-inflammatory-protein-longerScientists discover switching off inflammatory protein leads to...

   medicalxpress.com › news › 2024-07-scientists-inflammatory-protein-longer

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   17 lip 2024 · The scientists, working with colleagues at Duke-NUS Medical School in Singapore, tested the effects of IL-11 by creating mice that had the gene producing IL-11 (interleukin 11) deleted.

3. www.bbc.co.uk › news › articlesAnti-ageing 'supermodel granny' drug extends life in animal tests

   www.bbc.co.uk › news › articles

   17 lip 2024 · The drug, a manufactured antibody that attacks interleukin-11, is being trialled in patients with lung fibrosis. This is where the lungs become scarred, making it harder to breathe.

4. www.nature.com › articles › s41586/024/07701-9Inhibition of IL-11 signalling extends mammalian healthspan and...

   www.nature.com › articles › s41586/024/07701-9

   17 lip 2024 · IL-11 is identified as a key regulator of ERK–AMPK–mTORC1 signalling, metabolism, inflammation and age-related disease and lifespan in mouse and human.

5. www.sciencealert.com › blocking-one-protein-extends-lifespan-in-mice-by-up-to-25Blocking One Protein Extends Lifespan in Mice by Up to 25%, Study...

   www.sciencealert.com › blocking-one-protein-extends-lifespan-in-mice-by-up-to-25

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   24 lip 2024 · A protein called interleukin 11 (IL-11) appears to play a crucial role in aging, with scientists extending the lifespans of mice by up to 25 percent simply by blocking the molecule's effects. Could it work in humans?

6. www.nature.com › articles › d41586/024/02298-5Mice live longer when inflammation-boosting protein is blocked -...

   www.nature.com › articles › d41586/024/02298-5

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   17 lip 2024 · Heidi Ledford. Laboratory mice live longer when they have an immune protein called IL-11 blocked, a study has found. Credit: Panther Media GmbH/Alamy. A protein that promotes inflammation could...

7. www.newscientist.com › article › 2439800-anti-inflammatory-drug-extended-theAnti-inflammatory drug extended the lifespan of mice by 20 per...

   www.newscientist.com › article › 2439800-anti-inflammatory-drug-extended-the

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   17 lip 2024 · Blocking an inflammatory molecule known as interleukin-11 (IL-11) extends the lifespan of mice, suggesting that drugs inhibiting IL-11 may have anti-ageing effects in people, too.