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22 maj 2024 · The vegetative and minimally conscious states (MCS) are clinically defined syndromes. Importantly, prognosis for recovery can vary depending on the underlying etiology and differs between patients who have hypoxic-ischemic versus traumatic brain injury [7].
27 sty 2023 · Ischemic cell death occurs via 2 different pathways: necrosis and apoptosis. During hypoxia-ischemia of the brain, acute energy failure leads to loss of ion homeostasis where intracellular sodium and calcium accumulate, creating osmotic swelling, which can lead to cell lysis.
24 cze 2021 · Summary. Guideline-recommended treatment of HIBI includes early, optimal cardiopulmonary resuscitation to prevent primary brain injury, and targeted temperature management to mitigate secondary brain injury.
The principal findings are that ischemic brain volume and hypoxic brain volume are higher after TBI than in control participants. This finding was manifest by many small regions of hypoxic brain that were widely dispersed as small nonconfluent voxels scattered in the brain.
9 lut 2012 · Background: The outcome for patients with hypoxic–ischaemic brain injury (HIBI) is often poor. It is important to establish an accurate prognosis as soon as possible after the insult to guide management.
Background: The prediction of neurologic outcome is a fundamental concern in the resuscitation of patients with severe brain injury. Objective: To provide an evidence-based update on neurologic prognosis following traumatic brain injury and hypoxic-ischemic encephalopathy after cardiac arrest.
Overall, the prognosis is extremely poor and only a quarter of patients survive to hospital discharge, and often even then with severe neurological or cognitive deficits.
