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A frameshift mutation (also called a framing error or a reading frame shift) is a genetic mutation caused by indels (insertions or deletions) of a number of nucleotides in a DNA sequence that is not divisible by three.
Mutacja przesuwająca ramkę odczytu (ang. frameshift mutation) – mutacja genowa wywołana przez insercję bądź delecję jednego lub większej, niepodzielnej przez 3, liczby nukleotydów w kwasie nukleinowym. Ponieważ aminokwasy kodowane są przez tryplety nukleotydów (tworzące kodon) insercja lub delecja prowadzi do przesunięcia się ramki odczytu.
1 dzień temu · A frameshift mutation in a gene refers to the insertion or deletion of nucleotide bases in numbers that are not multiples of three. This is important because a cell reads a gene’s code in groups of three bases when making a protein.
27 kwi 2017 · Frameshift mutations are insertions or deletions in the genome that are not in multiples of three nucleotides. They are a subset of insertion-deletion (indel) mutations that are specifically found in the coding sequence of polypeptides.
2 cze 2022 · A frameshift mutation alters the reading frame of a coding gene and may produce frameshift proteins (frameshifts). Frameshifts have been considered mostly meaningless since they look completely different from the wild type and are often interrupted by many stop signals.
A frameshift mutation is a genetic mutation caused by a deletion or insertion in a DNA sequence that shifts the way the sequence is read.
Frameshift mutations are base additions or deletions within the coding region of a gene disturbing the reading frame so that the entire set of triplets downstream of the addition or deletion is altered.
