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Pharmacologically, digoxin has a dual mechanism of action through its inhibition of the cardiac myofibril Na + -K + ATPase. (6) This leads to increased intracellular Ca 2+ concentrations (4, 6) and in turn increased inotropy, which may summate to trigger repetitive electrical impulses.
19 maj 2024 · At therapeutic levels, digoxin can cause effects on the electrocardiogram, which must be differentiated from digoxin toxicity (see below). The optimal serum concentration of digoxin is 0.5 ng/ml to 1.0 ng/ml.
8 paź 2024 · ECG Features of Digoxin Toxicity. The classic digoxin toxic dysrhythmia combines: Supraventricular tachycardia (due to increased automaticity) Slow ventricular response (due to decreased AV conduction) Other common dysrhythmias associated with digoxin toxicity include:
We herein describe two cases with specific reference to the electrocardiographic changes induced by digoxin and discuss the predisposing factors for toxicity, recognition of possible toxicity and treatment approaches.
Digoksyna wpływa także na zjawiska elektrofizjologiczne serca. Wywiera ujemnie działanie chrono- i dromotropowe, co znaczy, że zmniejsza częstość rytmu serca oraz zwalnia przewodzenie w węźle przedsionkowo-komorowym.
Co zawiera i jak działa Digoxin Teva - tabletki? Migotanie przedsionków z szybką czynnością komór. Zaawansowana niewydolność serca (II–IV klasa wg NYHA).
21 sie 2023 · Cardiac glycosides have important positive inotropic, neurohormonal, and electrophysiologic actions, which are the basis for its use in two clinical situations: heart failure due to systolic dysfunction, and in certain supraventricular tachyarrhythmias.
