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Learn how to diagnose, stage, and treat CKD in dogs and cats based on the International Renal Interest Society (IRIS) recommendations. Find out about serum creatinine, blood pressure, proteinuria, and other diagnostic and therapeutic priorities for each stage of CKD.
We recommend that IRIS CKD Stage 1 patients with persistent proteinuria (UPC ≥ 0.5 for dogs or 0.4 for cats) are not only monitored and thoroughly investigated but also receive standard treatment for proteinuria as currently recommended for IRIS CKD Stages 2 to 4.
In dogs, chronic kidney disease is associated with aging, and in simple terms can be considered to be the 'wearing out' of the kidney tissues. The age of onset is often related to the size of the dog. For most small dogs, the early signs of kidney disease occur at about ten to fourteen years of age.
Early signs of CKD may be mild, even inapparent to the pet owner. Because isosthenuria and azotemia do not develop until 66% and 75% nephron loss, respectively, most renal function has been lost by onset of clinical signs. Common clinical signs include: Polyuria and compensatory polydipsia.
Diagnosing, Staging, and Treating Chronic Kidney Disease in Dogs and Cats. Chronic kidney disease (CKD) is diagnosed based on evaluation of all available clinical and diagnostic information in a stable patient. Following diagnosis of CKD, the IRIS Board recommends using serum creatinine or SDMA (ideally both) to stage CKD with substaging based ...
Dogs with CKD, as are humans and cats, are at risk for an acute decrease in kidney function, 16, 25 warranting characterization of the causes and prognostic factors. Better characterization of the disease might aid in preventing and treating this potentially fatal disorder.
1 mar 2009 · Chronic kidney disease (CKD) occurs over a period of months to years and is a leading cause of morbidity and mortality in dogs. Nephron damage associated with CKD is usually irreversible and can be progressive.
