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IgA Endomysial antibody (EMA): The EMA test has a specificity of almost 100%, making it the most specific test for celiac disease, although it is not as sensitive as the tTG-IgA test. About 5-10% of people with celiac disease do not have a positive EMA test.
20 gru 2021 · The EMA-IgA test is an important marker for celiac disease, portraying a 99% accuracy rate. This test is expensive and involves a high degree of technical precision. It is used as an accompanying test along with the routine tTG-IgA test to confirm the diagnosis of celiac disease.
The IgA endomysial antibody test (EMA) based on fluorescence testing on primate esophagus or human umbilical cord is based on antibody reactivity to tissue-bound TG-2. EMA is more labor-intensive and depends on personal judgment and experience.
13 kwi 2019 · Diagnostic testing, including serology and biopsy, should be performed on a gluten-containing diet. The diagnosis of CD is based on a combination of clinical, serological and histopathological data. In a group of children the diagnosis may be made without biopsy if strict criteria are available.
23 lip 2019 · The present review is timely and provides a thorough appraisal of various aspects characterizing celiac disease. Remaining challenges include obtaining a better understanding of still-unclear phenotypes such as slow-responsive, potential (minimal lesions) and seronegative celiac disease.
1 cze 2017 · Current evidence on the accuracy of tests used to diagnose celiac disease supports the excellent sensitivity and specificity of anti-tissue transglutaminase immunoglobulin A (tTG IgA) tests.
13 sty 2023 · The EMA test is most often used in people with classic celiac disease symptoms who have tested negative on less costly tTG and DGP tests. Celiac blood test results are usually returned within one to three days, but the EMA and celiac genetic test results may take longer.
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