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Parafollicular cells are pale-staining cells found in small number in the thyroid and are typically situated basally in the epithelium, without direct contact with the follicular lumen. They are always situated within the basement membrane, which surrounds the entire follicle.
The thyroid gland consists of two endocrine cell types, the follicular cells that produce the thyroid hormones thyroxine (T4) and triiodothyronine (T3), and the parafollicular C-cells that synthesize calcitonin.
5 gru 2022 · Parafollicular Cells (C–cells) These are also known as clear cells or light cells. The C stands for calcitonin or clear. These are large, polyhedral, pale-staining cells with oval and eccentric nuclei. They are widely distributed between follicular cells and their basement membrane.
Parafollicular cells, also known as C-cells, are a type of cells found in the thyroid gland that lie between the follicles. These cells are larger than the follicular epithelial cells and contain secretory granules that release calcitonin and somatostatin into adjacent capillaries.
13 lut 2023 · The thyroid gland comprises thyroid follicles that synthesize and store thyroid hormone. The epithelial cells, referred to as follicular cells or thyrocytes, surround the colloid in the lumen. The ultimo-branchial cells or neural cells accompanying them are the origins of the C-cells in the thyroid gland, which secrete the hormone calcitonin.[1]
Parafollicular cells (C cells) scattered throughout the thyroid gland synthesize, store, and secrete calcitonin (thyrocalcitonin). These cells are derived from neural crest cells that fuse with the thyroid gland.
30 paź 2023 · Another cell type that can be identified on histological preparations of thyroid tissue is parafollicular cells, also known as C (clear) cells. C-cells appear clear due to the fact that they are lightly stained on H&E preparation.