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  1. 8 lis 2021 · Systemic antibiotics present one of the alternative adjunctive therapies in nonsurgical periodontal treatment (NSPT). Different protocols have been proposed, but their indication and effectiveness are still controversial.

  2. All the antibiotics used in periodontal therapy, inhibit growth of the major periodontal pathogens P. gingivalis, C. rectus and Capnocytophaga. In direct contrast, none are particularly effective in the inhibition of E. corrodens (minocycline and doxycycline being best).

  3. An ideal antibiotic for use in prevention and treatment of periodontal disease should be specific for periodontal pathogens, allogenic and nontoxic, substantive, not in general use for treatment of other diseases, and inexpensive.

  4. 12 gru 2014 · Basic questions concerning the use of systemic antibiotics to treat periodontitis remain unanswered, such as: which drug (s) should be used; which patients would most benefit from treatment; which are the most effective protocols (i.e. doses and durations); and in which phase of the mechanical therapy should the drug (s) be administered?

  5. Good practice statement: The expert panel suggests dentists prescribe oral amoxicillin (500 mg, 3 times per d, 3-7 d) or oral penicillin V potassium (500 mg, 4 times per d, 3-7 d) ‡‡,§§,¶¶,##,∗∗∗ for immunocompetent adults with pulp necrosis and acute apical abscess with systemic involvement.†††.

  6. 1 wrz 2014 · The objective of the present paper is to discuss the appropriate use of systemic and local adjunctive antibiotics/antimicrobials in the management of periodontal diseases using a number of case studies to illustrate an evidence-based approach to treatment. Get full access to this article. View all access and purchase options for this article.

  7. Evidence synthesis: Adjunctive systemic antimicrobials have been evaluated both in aggressive and chronic periodontitis: in aggressive periodontitis, amoxicillin and metronidazole have been extensively studied, reporting clinical and microbiological benefits; in chronic periodontitis, different products are under scrutiny, such as azithromycin.

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