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The first step of this synthesis route to an N-arylformamidine as amitraz is the reaction of a substituted formamide, usually a dialkylformamide, with an aniline. [6] To gain amitraz N-methyl formamide and 2,4 dimethyl aniline hydrochloride can be used (figure 2).
4 kwi 2024 · Pszczoły. Zwalczanie warrozy pszczół: Co wiemy o amitrazie? W leczeniu warrozy pszczół wciąż duże znaczenie ma wykorzystanie tzw. twardej chemii. Sztandarowym przykładem substancji roztoczobójczej jest znana od dziesięcioleci amitraza. Warto napisać parę słów na temat tej substancji.
13 paź 2020 · Amitraz is metabolized into 2,4- and 2,6-disubstituted anilines in rats, which are further transformed into nitrosobenzenes (8). Metabolic degradation products in honey and beeswax were analyzed, and the metabolic degradation of amitraz into 2,4-dimethylformamidine (DMF) and N '- (2,4-dimethylphenyl)- N -methylformamidine (DMPF) was proposed (21).
2 kwi 2019 · Amitraz is a non-systemic acaracide and insecticide. Current maximum residue limits for amitraz are stated as ‘Amitraz including the metabolites containing the 2,4-dimethylaniline moiety’. Therefore, determination of amitraz and its all degradation products are important.
1 lip 2010 · Amitraz, 1,5-di-(2,4-dimethylphenyl)-3-methyl-1,3,5-tri-aza-penta-1,4-diene, is a member of formamidine pesticide family. It is an acaricide and insecticide indicated for control of ticks, mites, lice and other infestations on sheep, cattle and swine with good therapeutic results.
Amitraz and thiram are pesticides that have been shown to disrupt luteinizing hormone (LH) secretion in rats, albeit by different mechanisms. Amitraz acts via alpha-noradrenergic antagonism; whereas thiram inhibits norepinephrine synthesis.
1 sty 2015 · We developed a method for the hydrolysis of amitraz, and its degradation products 2,4-dimethylphenyl-N'-methylformamidine (DMPF) and 2,4-dimethylformamide (DMF) into 2,4-dimethylaniline (DMA), directly from QuEChERS extracts.
