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1 cze 1985 · To ascertain if zinc gluconate produced pain in genital herpes, we tested warm zinc gluconate aqueous solutions (2 3 5 m M) on genital herpetic lesions in four female subjects. The subjects reported that such solutions caused no pain, accelerated recovery, and were well appreciated.
Recurrent herpes labialis (RHL) is a common recurrent infective vesiculoulcerative disease. Topical and systemic administration of Zinc compounds has been indicated to have preventive and therapeutic effects.
With an HSV-1 isolate, 50 mM zinc gluconate or zinc lactate caused 100% inactivation, 15 mM caused 98 to 99% inactivation, and 5 mM caused 63 to 86% inactivation.
Topical 4% ZnSO 4 has been found to be most efficacious out of the three concentrations, without any side effects. Keywords: Herpes genitalis, new approach, zinc sulfate. Herpes genitalis is one of the commonest diseases in both developing as well as in developed countries.
1 cze 1985 · Zinc ions have been reported to be antiviral to herpes simplex viruses. A number of treatments using zinc are reviewed which illustrate the effects of topically applied zinc in reducing the duration and severity of human orolabial and genital infections.
Zinc salt solutions administered as topical microbicides provided significant protection against herpes simplex virus type 2 infection in a mouse vaginal challenge model. However, at the therapeutic concentration, the salt solutions caused sloughing of sheets of vaginal epithelial cells.
6 sie 2013 · Results: Zinc sulphate, zinc citrate, zinc stearate and zinc gluconate demonstrated similar potentiated virucidal activity with PRE against HSV-1 by up to 4-fold.
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