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  1. To inform clinical practice about the health effects of menopausal hormone therapy, calcium plus vitamin D supplementation, and a low-fat dietary pattern, the Women’s Health Initiative (WHI) enrolled 161 808 postmenopausal US women (N = 68 132 in the clinical trials) aged 50 to 79 years at baseline from 1993 to 1998, and followed them up for ...

  2. 18 wrz 2019 · In 1998, the Women’s Health Initiative (WHI) was started, which was the largest randomized study to date that was aimed at evaluating the effect of HRT on the most common causes of death and disability in postmenopausal women, such as cardiovascular disease, cancer, and osteoporosis.

  3. 1 sie 2023 · The Women's Health Initiative (WHI) placebo-controlled randomised study examined the effects of continuous combined or estrogen-only MHT on the risk of non-communicable diseases (NCDs) in post-menopausal women.

  4. 2 paź 2013 · The Women’s Health Initiative (WHI) hormone therapy (HT) trials were designed to determine the benefits and risks of HT taken for chronic disease prevention by predominantly healthy postmenopausal women. 1–3 Although originally prescribed primarily to treat vasomotor symptoms, menopausal HT had been increasingly viewed as a way to prevent ...

  5. 28 maj 2024 · To inform clinical practice about the health effects of menopausal hormone therapy, calcium plus vitamin D supplementation, and a low-fat dietary pattern, the Women's Health Initiative (WHI) enrolled 161 808 postmenopausal US women (N = 68 132 in the clinical trials) aged 50 to 79 years at baseline from 1993 to 1998, and followed them up for up ...

  6. 1 kwi 2023 · Importance and objective: The menopausal hormone therapy (MHT) association with breast cancer has been controversial for more than 40 years. Most recently, findings from cohort studies have been discordant compared with those from the Women's Health Initiative (WHI) randomized trials.

  7. The Women’s Health Initiative (WHI) hormone therapy trials were designed to assess the benefits and risks of menopausal hormone therapy taken for chronic disease prevention by predominantly healthy postmenopausal women. 1-3 The double-blinded, placebo-controlled, randomized clinical trials, conducted among US postmenopausal women aged 50 to ...

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