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Vancomycin is an antibiotic drug used to treat serious, life-threatening infections by gram-positive bacteria that are resistant to less-toxic agents. The reference range for vancomycin trough...
- Staphylococcus Aureus Infection
Both community-associated and hospital-acquired infections...
- Creatinine
Creatinine is critically important in assessing renal...
- Staphylococcus Aureus Infection
In adults with normal renal function, the half-life of vancomycin is 6 to 12 hours. 2 If steady state occurs within five half-lives (that is, in 30 to 60 hours), a vancomycin trough before the fourth dose is acceptable in a patient receiving every 8- or 12-hour dosing.
22 lut 2023 · • Select a trough range as approximately +/- 2 of the trough level corresponding to target AUC, assuming the AUC is not already at the upper or lower limits. Please use clinical discretion.
2 sie 2024 · Appropriate dosing and administration of vancomycin requires consideration of the pathogen and its susceptibility, type and severity of infection, patient weight, and kidney function . The optimal approach to vancomycin dosing and monitoring for invasive methicillin-resistant S. aureus (MRSA) infections is a subject of ongoing controversy and ...
6 lut 2021 · A meta-analysis of AKI incidence indicated significantly higher incidence rates for trough concentrations ≥15 μg/mL compared to those for concentrations < 15 μg/mL [8, 10, 11]. In the clinical setting, dosage regimens based on the trough level is still used because it is a conventional method.
1 sie 2009 · Trough serum vancomycin concentrations are the most accurate and practical method of monitoring the effectiveness of vancomycin. Trough serum concentrations should be obtained just before the fourth dose, at steady-state conditions.
24 mar 2023 · Vancomycin is used to treat and prevent various bacterial infections caused by gram-positive bacteria, including methicillin-resistant (MRSA). It is also effective for streptococci, enterococci, and methicillin-susceptible (MSSA) infections. Vancomycin has numerous FDA-approved and off-label clinical uses. FDA-approved Clinical Uses.
