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24 sie 2016 · The circuits through which serotonin regulates mood are not well understood. Here Thomas Kash and colleagues describe a mechanism by which serotonin induces an anxiety-like state in mice.
In adulthood, serotonin reuptake inhibitors act through the same receptor to stimulate neurogenesis and reduce anxiety-like behaviors. These studies highlight that the complex serotonin system likely plays various roles in the regulation of anxiety both during development and in adulthood.
In this book, the author summarizes the latest findings regarding the role of serotonin in modulating the activity of brain regions which organize behavioral patterns associated with fear, anxiety and stress.
The wide use of serotonin reuptake inhibitors and serotonin receptor agonists in anxiety disorders has suggested a key role for the modulatory neurotransmitter in anxiety. However, serotonin’s specific role is still uncertain. This article reviews the literature concerning how and where serotonergic agents modulate anxiety.
13 sty 2021 · Serotonin receptor 4 (5-HT 4 R) plays an important role in regulating mood, anxiety, and cognition, and drugs that activate this receptor have fast-acting antidepressant (AD)-like effects...
There is a high comorbidity between anxiety (especially generalized anxiety disorders or panic disorders) and depressive disorders. Additionally, anxiety disorders are often associated, which renders treatment even more complex for nonspecialists. As a result, anxiety disorders often remain underdiagnosed and undertreated in primary care. 3
8 maj 2023 · The serotonergic hypothesis, proposed by Professor Coppen in 1967, suggests that 5-hydroxytryptamine (5-HT) deficiency is the main underlying cause of depression and anxiety, a notion that was further supported by numerous studies.
