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  1. Learn how a replication fork is a region where DNA double helix is unwound and separated to synthesize a new double helix. Find out the roles of helicase, primase, DNA polymerase, and other enzymes and proteins in the process.

    • Replication Fork

      The active region of DNA replication where the two strands...

    • DNA

      an abbreviation for Deoxyribonucleic Acid, the material that...

    • Helicase

      The enzyme responsible forming the replication fork during...

    • Printer-friendly Version

      So before DNA polymerase can begin working, primase * (a...

    • Nucleotides

      Nucleotides are the building blocks of DNA and RNA....

    • Primase

      The enzyme that initiates DNA replication by adding a short...

  2. A replication fork is a multiprotein complex that unwinds and synthesizes DNA during cell cycle. Learn how replication forks stall, restart and respond to DNA damage with examples and illustrations.

  3. 17 mar 2022 · Learn about the process of DNA replication, which involves the unwinding of the double helix, the synthesis of new strands, and the separation of the replicated DNA. The replication fork is the site where DNA synthesis occurs and where the two new strands are formed.

  4. 1 mar 2013 · Here, we describe the functions of the major replisome components, as well as some of the obstacles to efficient DNA replication that the replisome confronts. Together, this review summarizes current understanding of the vastly complicated task of replicating eukaryotic DNA.

  5. Two replication forks moving in opposite directions on a circular chromosome. An active zone of DNA replication moves progressively along a replicating DNA molecule, creating a Y-shaped DNA structure known as a replication fork: the two arms of each Y

  6. 29 sty 2013 · Abstract. Eukaryotic cells must accurately and efficiently duplicate their genomes during each round of the cell cycle. Multiple linear chromosomes, an abundance of regulatory elements, and chromosome packaging are all challenges that the eukaryotic DNA replication machinery must successfully overcome.

  7. Learn what a replication fork is, how it forms, and what happens at it during DNA replication. Find out the difference between leading and lagging strands, and the enzymes involved in DNA unwinding and synthesis.

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