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4 mar 2021 · Pathogenesis—or “origin of disease”—is the study of the processes that give rise to physiologic dysfunction and illness. In the case of COVID-19, it is the study of virus-induced mischief—how SARS-CoV-2 interacts with various cells, tissues, and organs to cause COVID-19.
McKeown's The origins of human disease was published in 1988, and was a bold attempt at classifying all diseases in only three categories: prenatal diseases (all diseases manifested before birth), diseases of poverty (diseases manifested after birth that are attributable to deficiencies or hazards related to lack of the essentials for life ...
The search for the causes (etiologies) of human diseases goes back to antiquity. Hippocrates, a Greek physician of the 4th and 5th centuries bce, is credited with being the first to adopt the concept that disease is not a visitation of the gods but rather is caused by earthly influences. Scientists have since continually searched for the causes ...
17 maj 2007 · Analysis of what we know of the origins of 10 tropical and 15 temperate infectious diseases reveals that animals were the source of the majority of important human diseases in the recent...
The natural history of disease is the course a disease takes in individual people from its pathological onset ("inception") until its resolution (either through complete recovery or eventual death). [1]
6 sty 2021 · Nearly all genetic variants that influence disease risk have human-specific origins; however, the systems they influence have ancient roots that often trace back to evolutionary events long...
8 sty 2020 · A primary goal of human genetics is to identify DNA sequence variants that influence biomedical traits, particularly those related to the onset and progression of human disease.
