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  1. The MDRD GFR Equation estimates glomerular filtration rate based on creatinine and patient characteristics.

  2. CKD-EPI Equations for Glomerular Filtration Rate (GFR) Estimates GFR based on serum creatinine, serum cystatin C, or both. IMPORTANT. The 2021 CKD-EPI equation is now the recommended standard. This version does not include race, as do the 2009 and 2012 CKD-EPI creatinine and creatinine-cystatin C equations.

  3. The glomerular filtration rate is the flow rate of filtered fluid through the kidney. The creatinine clearance rate ( C Cr or CrCl ) is the volume of blood plasma that is cleared of creatinine per unit time and is a useful measure for approximating the GFR.

  4. Glomerular filtration rate (GFR) is the best overall index of kidney function. Normal GFR varies according to age, sex, and body size, and declines with age.

  5. The original CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) equation was developed in 2009 in an effort to create a more precise formula to estimate glomerular filtrate rate (eGFR) from serum creatinine and other readily available clinical parameters, especially at when actual GFR is >60 mL/min per 1.73m 2.

  6. Overview of recommended glomerular filtration rate (GFR) equations for calculating estimated GFR in adults and children and best practices for reporting eGFR.

  7. Glomerular Filtration Rate Estimate by CKD-EPI Equation. In these topics. Overview of Disorders of Fluid Volume. Evaluation of the Renal Patient. Brought to you by Merck & Co, Inc., Rahway, NJ, USA (known as MSD outside the US and Canada) — dedicated to using leading-edge science to save and improve lives around the world.

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