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  1. Dogs and cats may still have PU and PD despite identification of concentrated urine; possible differentials include disorders causing an osmotic diuresis (e.g., diabetes mellitus), psychogenic polydipsia and disorders in the regulation of AVP secretion.

  2. Key Points. Diabetes insipidus is rare in dogs and cats and results from deficiency of ADH or lack of response to ADH, or it can be secondary to brain trauma. Diagnosis can be achieved through administration of a water deprivation test or by showing an increase in urine osmolality after ADH supplementation.

  3. Diabetes insipidus and psychogenic polydipsia may be differentiated by a water-deprivation test. It is important to recognise that the end point must be detectable dehydration, which may take many hours in an animal with normal urine concentrating capacity.

  4. 1 wrz 2022 · If your veterinarian suspects a rare disease called diabetes insipidus, which causes the body to make too much urine, other tests will be needed. Diabetes insipidus is not related to diabetes mellitus, which is only a problem with blood sugar.

  5. Nephrogenic diabetes insipidus is a physiological condition in which the kidneys fail to concentrate urine despite adequate amounts of antidiuretic hormone (ADH). Central (pituitary-dependent) diabetes insipidus develops when there is a lack of ADH production.

  6. Diabetes mellitus (DM) is a common disease encountered in canine and feline medicine. The 2018 AAHA Diabetes Man- agement Guidelines for Dogs and Cats revise and update earlier guidelines published in 2010.

  7. Diabetes insipidus (DI) is characterized by an absolute or relative lack of ADH. Clinically, patients with DI have intense thirst and failure to concentrate urine. Two forms of DI are recognized. The first form, central DI (CDI), occurs when there is failure of ADH production from the hypothalamus or pituitary gland.

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