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Protein crystallization is the process of formation of a regular array of individual protein molecules stabilized by crystal contacts. If the crystal is sufficiently ordered, it will diffract. Some proteins naturally form crystalline arrays, like aquaporin in the lens of the eye. [1] [2]
1 sty 2014 · The crystallization of proteins, nucleic acids and large biological complexes, such as viruses, depends on the creation of a solution that is supersaturated in the macromolecule but exhibits conditions that do not significantly perturb its natural state.
30 sty 2008 · Determining the structure of biological macromolecules by X-ray crystallography involves a series of steps: selection of the target molecule; cloning, expression, purification and...
16 paź 2017 · The topologies of carefully selected high-quality protein crystal structures have been determined and compared to those of a large set of small molecule crystal structures.
2 cze 2017 · A large number of protein structures have now been solved using crystals grown from polyethylene glycol. These confirm that the protein molecules are in as native condition in this medium as in any other.
6 maj 2015 · Selected protein crystal structures from the PDB in cartoon format and alphabetical order, overlaid on a diffraction image (provided by E. Lowe), with a central bright-field image of a...