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9 sie 2023 · Although more studies are needed, some research suggests that CoQ10 may help reduce low-density lipoprotein (LDL) cholesterol and total cholesterol levels in people with diabetes, lowering their risk of heart disease.
13 lis 2014 · Therefore, the precise effect (s) of CoQ10 supplementation has not been established. In this study, we systematically review all the published trials on CoQ10 supplementation and assess its overall efficacy on muscle pain and elevated plasma CK activity, as measures of statin-induced myalgia.
I suggest that a randomized trial of CoQ10 supplementation be conducted, testing whether a dosage of 1 g twice per day ameliorates statin-induced myopathy in order to eliminate the possibility of undersupplementation.
13 lis 2014 · Effects of CoQ10 supplementation on plasma lipoprotein lipid, CoQ10 and liver and muscle enzyme levels in hypercholesterolemic patients treated with atorvastatin: a randomized double-blind study
17 maj 2021 · Coenzyme Q 10 (CoQ 10) is an essential cofactor in oxidative phosphorylation (OXPHOS), present in mitochondria and cell membranes in reduced and oxidized forms. Acting as an energy transfer molecule, it occurs in particularly high levels in the liver, heart, and kidneys.
CoQ10 supplementation reduces oxidative stress and mortality from cardiovascular causes and improves clinical outcome in patients undergoing coronary artery bypass graft surgery, prevents the accumulation of oxLDL in arteries, decreases vascular stiffness and hypertension, improves endothelial dysfunction by reducing the source of ROS in the vas...
A third possible explanation for the lack of effectiveness of CoQ10 in this study and previous studies is that the dose of CoQ10 was too low. The adult human body contains approximately 2 g of CoQ10, ... I. Mayo Clin. Proc. 90(3), 419–420 (2015). [Google Scholar] 26. Zhang Y, Turunen M, Appelkvist EL. Restricted uptake of dietary coenzyme Q ...
