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Generic Name: cephalexin. Brand Name: Apo-Cephalex (CAN), Biocef, Keflex, Novo-Lexin (CAN), Nu-Cephalex (CAN) Classification: Antibiotic, Cephalosporin (first generation) Pregnancy Category B. Dosage & Route Adults. 1–4 g/day in divided doses; 250 mg PO q 6 hr usual dose.
Because of these similarities in chemical structure, some clients who have severe allergies to penicillins may experience cross-sensitivity to cephalosporins. Nurses should review the type and severity of a client’s previous reaction to penicillin to determine if administering cephalosporin is appropriate.
Cephalosporin Nursing Antibiotic Pharmacology Review. This is a large group of beta-lactam antibiotics used to target a variety of gram-positive and gram-negative bacteria. There are five generations of Cephalosporins currently. These antibiotics are similar to another group of beta-lactam antibiotics called the Pencillins.
Cephalosporins are a large group of broad-spectrum antibiotics, which can be used to treat a wide variety of bacterial infections, including meningitis, pneumonia, urinary tract infections, and sepsis. These antibiotics get their name from Cephalosporium acremonium, a fungus from which they are derived.
Nursing Considerations. • Contraindicated with cephalosporin and serious penicillin allergies. • May need lead to seizures, pseudomembranous colitis, diarrhea, phlebitis. at IV site, anaphylaxis. • Assess infection and allergies. • Obtain cultures prior to therapy. • Monitor bowel function. • May lead to superinfection.
Indications: Cephalosporins are used to treat skin and skin-structure infections, bone infections, genitourinary infections, otitis media, and community-acquired respiratory tract infections. Nursing Considerations: Clients who are allergic to pencillins may also be allergic to cephalosporins.
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