Search results
14 mar 2023 · You may have a high MCV because you have a lot of immature red blood cells (reticulocytes) in your blood. Reticulocytes are larger than fully mature red blood cells. Causes of macrocytosis include: Nutritional deficiencies: Your body needs nutrients, like vitamin B12 and folate (vitamin B9), to make healthy red blood cells. Your red blood cells ...
High MCV is indicative of a larger-than-average size of red blood cells (RBCs), which could be due to: Folate deficiency is the most common cause of high MCV. Vitamin B12 deficiency; Liver disease; Hypothyroidism; Aplastic anemia (anemia due to bone marrow development failure) Myelodysplastic syndrome (a group of disorders in which RBCs do not ...
25 sty 2023 · Common causes of macrocytosis include: Vitamin B-12 deficiency. Folate deficiency. Liver disease. Alcoholism. Hypothyroidism. A side effect of certain medications, such as those used to treat cancer, seizures and autoimmune disorders.
26 wrz 2022 · An elevated mean corpuscular hemoglobin accompanies most elevated MCV reports. The elevation of MCV and/or mean corpuscular hemoglobin suggests macrocytosis. In some cases, discovering macrocytosis may not necessitate further testing or treatment.
16 lis 2008 · Causes of macrocytosis include alcohol intake, vitamin B12 and folate deficiency, chemotherapy and other drugs, hemolysis or bleeding, liver dysfunction, myelodysplastic syndrome (MDS), and hypothyroidism. Approximately 10% of patients will have unexplained macrocytosis after laboratory evaluation.
9 maj 2024 · Macrocytosis is a descriptive term for red blood cell (RBC) size larger than the normal range. It may be caused by abnormalities of RBC production in the bone marrow, altered RBC membrane composition, or an increase in the percentage of reticulocytes, which are larger than mature RBCs.
1 lut 2009 · History and physical examination, vitamin B12 level, reticulocyte count, and a peripheral smear are helpful in delineating the underlying cause of macrocytosis.
