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General: anatomy & histology-adrenal cortex, medulla & paraganglia books features to report-adrenal cortical carcinoma features to report-pheochromocytoma / paraganglioma staging-adrenal cortical carcinoma staging-neuroblastic tumors staging-pheochromocytoma & paraganglioma WHO classification WHO reporting system for adrenal gland cytopathology ...
13 gru 2021 · Adrenal gland, left, adrenalectomy: Adrenal cortical carcinoma with the following features: Tumor size: 8.5 cm x 7.5 cm x 7 cm. Tumor (gland) weight: 228 g. Tumor extent: tumor invades through the adrenal capsule. Histologic type: focal myxoid and oncocytic features. Histologic grade: low grade.
27 paź 2022 · Radiology description. Mostly unilateral and solitary; rarely bilateral (5%) Rounded tumor mainly comprised of macroscopic fat with a variable proportion of myeloid components. Myeloid components can be seen as a cloudy pattern, solid strands or forming a separate solid nodule within the fat.
1 lip 2016 · Accessed November 11th, 2024. Definition / general. Metastatic tumors more common than primary tumors in adrenal gland. Common at autopsy, usually bilateral. Most common primary sites are breast, lung, kidney, stomach, pancreas, ovary and colon. Usually does not affect adrenal function. May cause adrenal insufficiency if extensive (replacing 80 ...
12 lip 2022 · C. SF1. Adrenal rests are generally composed of both clear adrenocortical cells and compact ones. However, the zonation is frequently blurred and only composed of either clear or compact cells. Nests of adrenal cortical cells are, in general, immunohistochemically positive for SF1, MelanA and inhibin A at both eutopic and ectopic sites.
3 sty 2023 · Synaptophysin, chromogranin and S100 are positive in pheochromocytoma. AE1 / AE3, CK7 and TTF1 are consistent with metastatic lung adenocarcinoma. AE1 / AE3, CK7 and ER are consistent with metastatic breast carcinoma. MelanA, inhibin A are calretinin are seen in adrenal cortical adenoma / carcinoma.
1 kwi 2015 · ALK amplification associated with poor prognosis. 6-10% of neuroblastomas have somatic ALK mutations. 3-4% of neuroblastomas have high risk ALK amplifications. MYCN amplification (≥ 10 copies for diploid genome or >4 fold signal relative to chromosome 2) associated with poor prognosis. Occurs in ~22% of tumors.
27 gru 2021 · Adrenal cortical carcinoma with the following features: Tumor size: 15 cm x 11 cm x 10 cm. Tumor (gland) weight: 450 g. Tumor extent: organ confined. Histologic type: pure oncocytic variant. Histologic grade: low grade. Necrosis: present. Lymphovascular invasion: absent. Margins: free of tumor.
Definition / general. Neoplasm of neuroectodermal origin comprised of mixture of neuroblasts and ganglion cells in varying proportions. Divided into stroma rich (well differentiated, intermixed, nodular) and stroma poor categories depending on amount of Schwannian, spindle cell stroma. Intermixed: composite tumor in the stroma rich category.
6 kwi 2022 · Diagnostic gold standard test for primary adrenal insufficiency. Cosyntropin: synthetic form of the biologically active region of ACTH. Standard dose: 250 μg for adults and children ≥ 2 years of age, 125 μg for children < 2 years of age and 15 μg/kg for infants. Cortisol levels measured at baseline and 30 and 60 minutes after cosyntropin ...
