Search results
Idiopathic acquired aplastic anemia (aAA) is a rare, life threatening bone marrow failure syndrome characterized by cytopenias and a hypocellular bone marrow. Aplastic anemia (AA) is classified as either inherited or acquired.
1 kwi 2019 · Idiopathic acquired aplastic anemia is an autoimmune disease that affects mainly young people, usually around the second to third decades of life, with a small increase in presentation also noted in the fifth to sixth decades. Based on the peripheral blood counts, aplastic anemia can be moderate, severe or very severe.
22 cze 2021 · Establishing a diagnosis of aplastic anemia (AA) can be challenging, but it is absolutely critical to appropriate management, especially differentiating between acquired and inherited forms of the disease.
11 lis 2017 · Acquired aplastic anemia (AA) is a rare, life-threatening bone marrow failure (BMF) disorder that affects patients of all ages and is caused by lymphocyte destruction of early hematopoietic cells.
16 mar 2017 · Acquired severe aplastic anemia (SAA) is a rare hematologic disease associated with significant morbidity and mortality. Immune destruction of hemopoietic stem cells plays an important role in pathogenesis, as shown by successful treatment with immunosuppressive agents, leading to transfusion independence or complete recovery of peripheral ...
8 cze 2022 · Aplastic anemia (AA) is a life-threatening form of bone marrow failure which, if untreated, is associated with very high mortality. AA refers to pancytopenia in association with bone marrow hypoplasia/aplasia, most often due to immune injury to multipotent hematopoietic stem cells.
Idiopathic acquired aplastic anemia is a rare, life-threatening bone marrow failure syndrome characterized by cytopenias and hypocellular bone marrow. The pathophysiology is unknown; the most favored model is of a dysregulated immune system leading to autoreactive T-cell destruction of hematopoietic ….
